BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Region Report

Basic Info

Region Name	18q22
Chromosome Position	chr18:63900000-75400000
No. of Studies (Positive/Negative/Trend)	3(1/1/1)

Region related studies (count: 3)

Reference	Markers	Statistical Values	Author Comments	Result Category
Schulze, T. G.,2003	D18S1112, D18S61, D18S1125, D18S1091, D18S485, D18S1106, D18S541, D18S469, D18S879, D18S882, D18S486, D18S58	Multipoint Linkage Analysis: For marker D18S1112, Paternal L...... Multipoint Linkage Analysis: For marker D18S1112, Paternal LOD = 1.39, Maternal LOD = -0.45, MLOD = 0.95; For marker D18S61, Paternal LOD = 3.86, Maternal LOD = -1.73, MLOD = 2.55; For marker D18S1125, Paternal LOD = 4.4, Maternal LOD = -1.13, MLOD = 3.51; For marker D18S1091, Paternal LOD = 4.5, Maternal LOD = -0.98, MLOD = 3.73; For marker D18S485, Paternal LOD = 4.36, Maternal LOD = -1.63, MLOD = 3.14; For marker D18S1106, Paternal LOD = 4.31, Maternal LOD = -1.62, MLOD = 3.1; For marker D18S541, Paternal LOD = 5.42, Maternal LOD = -2.11, MLOD = 4.07; For marker D18S469, Paternal LOD = 5.22, Maternal LOD = -1.9, MLOD = 3.99; For marker D18S879, Paternal LOD = 4.74, Maternal LOD = -1.65, MLOD = 3.93; For marker D18S882, Paternal LOD = 3.99, Maternal LOD = -1.87, MLOD = 3.14; For marker D18S486, Paternal LOD = 2.83, Maternal LOD = -1.17, MLOD = 2.15; For marker D18S58, Paternal LOD = 2.81, Maternal LOD = -1.06, MLOD = 2.24 More...	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
Lambert, D.,2005	D18S48, D18S474	Linkage analysis: For marker D18S48, Multipoint MLS = 1.46(n...... Linkage analysis: For marker D18S48, Multipoint MLS = 1.46(narrow), 0.47(intermediate), 0.59(broad); Two point LOD score = 0.79(narrow), 0.22(intermediate), 0.22(broad); For marker D18S474, Two point LOD score = 0.55(narrow), 0.04(intermediate), 0(broad) More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
McInnis, M. G.,2003(b)	D18S878	Linkage analysis: Model BP, NPL = 2.9, P-value = 0.004, LOD(...... Linkage analysis: Model BP, NPL = 2.9, P-value = 0.004, LOD(ASM) = 1.8 More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend

Region related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CCDC102B	coiled-coil domain containing 102B	18q22.1	1(0/1/0)
CDH7	cadherin 7, type 2	18q22.1	1(0/0/1)

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Region: chr18:63900000..75400000 View in gBrowse