Gene Report

Basic Info
Approved Symbol TPX2
Previous Symbol C20orf2, C20orf1
Symbol Alias p100, DIL-2
Approved Name TPX2, microtubule-associated
Previous Name chromosome 20 open reading frame 1, "TPX2, microtubule-associated, homolog (Xenopus laevis)"
Location 20q11.2
Position chr20:31739271-31801805, 1
External Links HGNC: 1249
Entrez Gene: 22974
Ensembl: ENSG00000088325
UCSC: uc002wwp.1
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Drago, A., 2016 Freq(Significant SNPs/total SNPs%)=0.06. Encodes form TPX2 protein that is required for normal assembly of microtubules during apoptosis. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 18)

GO terms by PBA (count: 1)

GO terms by database search (count: 17)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 1)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 1)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr20:31739271..31801805 View in gBrowse
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