Gene Report

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Basic Info

Approved Symbol	THSD4
Symbol Alias	FVSY9334, PRO34005, FLJ13710, ADAMTSL6
Approved Name	thrombospondin, type I, domain containing 4
Location	15q23
Position	chr15:71096952-71783383, 1
External Links	HGNC: 25835 Entrez Gene: 79875 Ensembl: ENSG00000187720 UCSC: uc002atb.1
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Johnson, C.,2009		Monte-Carlo Simulation P-value = 0.0028. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 5)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0004222	metalloendopeptidase activity	molecular function	IEA	8

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0001527	microfibril	cellular component	IEA	2
GO:0048251	elastic fiber assembly	biological process	IEA	1
GO:0006508	proteolysis	biological process	IEA	34
GO:0070062	extracellular vesicular exosome	cellular component	IDA[19199708]	176

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 15	chr15:0-101991189	2 (0/2/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr15:71096952..71783383 View in gBrowse