Gene Report

Basic Info
Approved Symbol TACC3
Symbol Alias ERIC1
Approved Name transforming, acidic coiled-coil containing protein 3
Location 4p16.3
Position chr4:1721490-1745176, 1
External Links HGNC: 11524
Entrez Gene: 10460
Ensembl: ENSG00000013810
UCSC: uc003gdo.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Drago, A., 2016 Freq(Significant SNPs/total SNPs%)=0.14. Encodes for a member of the transforming acidic colied-coil protein family. It is involved in the microtubule-dependent coupling of the nucleus and the centrosome and regulates centrosome-mediated inter kinetic nuclear migration (INM) of neural progenitors. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 15)

GO terms by PBA (count: 1)

GO terms by database search (count: 14)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 4)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr4:1721490..1745176 View in gBrowse
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