Gene Report

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Basic Info

Approved Symbol	RNF219
Previous Symbol	C13orf7
Symbol Alias	FLJ13449
Approved Name	ring finger protein 219
Previous Name	chromosome 13 open reading frame 7
Location	13q31.1
Position	chr13:78614291-78659179, -1
External Links	HGNC: 20308 Entrez Gene: 79596 Ensembl: ENSG00000152193 UCSC: uc001vkw.1
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Sklar, P., 2008	SNP: rs1341139	No significant association of this gene was observed in BD.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 3)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005515	protein binding	molecular function	IPI[25416956]	563
GO:0008270	zinc ion binding	molecular function	IEA	77
GO:0048026	positive regulation of mRNA splicing, via spliceosome	biological process	IEA	1

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs1341139	chr13:78967053 - 78967053(1)		1(0/1/0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
13q21-33	chr13:54700000-109600000	1 (0/0/1)
13q22-32	chr13:72800000-101100000	1 (0/0/1)
13q31-q34	chr13:78500000-114364328	1 (0/0/1)
Chr 13	chr13:0-114364328	1 (0/0/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr13:78614291..78659179 View in gBrowse