BDgene

Gene Report

Basic Info
Approved Symbol NEFM
Previous Symbol NEF3
Symbol Alias NFM, NF-M
Approved Name neurofilament, medium polypeptide
Previous Name neurofilament, medium polypeptide 150kDa
Location 8p21
Position chr8:24913012-24919098, 1
External Links HGNC: 7734
Entrez Gene: 4741
Ensembl: ENSG00000104722
UCSC: uc003xed.4
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Fallin, M. D.,2005 1 SNP typed, all SNP or haplotype P-value > 0.05 in BP and SZ/SZA.. This gene is not suggestive to BP. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 12)

GO terms by PBA (count: 0)

GO terms by database search (count: 12)


Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)


Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 3)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 1)


Gene relationship with MDD

View in gBrowse

Region: chr8:24913012..24919098 View in gBrowse
View in gBrowse