BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Other Variant Report

Basic Info

Name	SLC12A6 32418760(G/A)
Type	point mutation
Related Gene	SLC12A6
No. of Study	1 (Positive: 1; Negative 0; Trend: 0)
Overlap with SZ?	YES
Overlap with MDD?	NO

Variant related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Meyer, J.,2005	G/A		For Bipolar disorder vs. controls:Allele, Exact test, P-value < 0.0001, Odds ratio=9.29 (2.76-31.31);genotype, Exact test, P-value = 0.0000, Odds ratio=(2.87-33.57).For All cases vs.controls:Allele, X² test, 1 d.f., X²=11.63, P-value = 0.0007, Odds ratio=5.72 (1.85-17.68);genotype, Armitage trend test, Z=-3.44, P-value = 0.0006, Odds ratio=5.90 (1.89-18.37).	Significant associations were found in BPD patients and all ..... More Significant associations were found in BPD patients and all cases. Less	Positive

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Meyer, J.,2005	For Schizophrenia vs. controls:Allele, Exact test, P-value = 0.0596, Odds ratio=3.54 (0.94-13.31) ;genotype, Exact test, P-value = 0.0586, Odds ratio=3.60 (0.95-13.65)	No significant associations were found in SZ.	Negative

Overlap with MDD from cross-disorder studies (count: 0)