BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Other Variant Report

Basic Info

Name	SLC12A6 32416574(G/A)
Type	point mutation
Related Gene	SLC12A6
No. of Study	1 (Positive: 1; Negative 0; Trend: 0)
Overlap with SZ?	YES
Overlap with MDD?	NO

Variant related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Meyer, J.,2005	G/A		For Bipolar disorder vs. controls:Allele, Exact test, P-value = 0.0051, Odds ratio=8.26 (1.95-34.97);genotype, Exact test, P-value = 0.0049, Odds ratio=8.53 (1.99-36.56) For All cases vs.controls:Allele, Exact test, P-value = 0.0053, Odds ratio=5.69 (1.53-21.16);genotype, Exact test, P-value = 0.0051, Odds ratio=5.81 (1.55-21.74)	Significant associations were found in BPD patients and all ..... More Significant associations were found in BPD patients and all cases. Less	Positive

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Meyer, J.,2005	For Schizophrenia vs. controls:Allele, Exact test, P-value = 0.0678, Odds ratio=4.10 (0.91-18.46);genotype, Exact test, P-value = 0.0671, Odds ratio=4.12 (0.92-18.86)	No significant associations were found in SZ.	Negative

Overlap with MDD from cross-disorder studies (count: 0)