BDgene

Other Variant Report

Basic Info
Name NRG1 exon 11 Val>Leu
Type point mutation
Location exon 11
No. of Study 1 (Positive: 0; Negative 1; Trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO

Variant related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Moon, E.,2011 Val>Leu For BD:Recessive model:Yates Chi-Square/P-value = 0.68/0.40;Dominant model:Fisher exact P-value = 0.077 No significant association was observed. Negative

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Moon, E.,2011 For SZ:0.68/0.40 model:Pearson Chi-Square/P-value = 0.91/0.34, Yates Chi-Square/P-value = 0.04/0.84, Pearson Chi-Square/P-value = 0.12/0.72;Dominant model:Fisher exact P-value = 1 No significant association was observed. Negative

Overlap with MDD from cross-disorder studies (count: 0)