BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Other Variant Report

Basic Info

Name	NDUFV2 -3245T>C
Type	point mutation
Related Gene	NDUFV2
No. of Study	1 (Positive: 1; Negative 0; Trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Variant related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Washizuka, S., 2004	T>C		genotypic P-value = 0.14, allelic P-value = 0.32 of BP total in Japanese, genotypic P-value = 0.80, allelic P-value = 0.61 of BPI in Japanese, genotypic P-value = 0.002, allelic P-value = 0.20 of BPII in Japanese, genotypic P-value = 0.01, allelic P-value = 0.38 among patients with BPI, BPII, and controls; TDT P-value = 0.15, X²=2	The -3542G> A, -3245T>G, and -2694A>G polymorphisms showed s..... More The -3542G> A, -3245T>G, and -2694A>G polymorphisms showed significant genotypic association with BDII. These SNPs tended to be associated with BD or BDII even after Bonferroni correction. We could not detect any allele that was significantly overtransmitted from patients to affected offspring in the NIMH trio samples of BD. Less	Positive

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)