Study Report

Basic Info
Citation Etain, B., F. Mathieu, et al. (2006). "Genome-wide scan for genes involved in bipolar affective disorder in 70 European families ascertained through a bipolar type I early-onset proband: supportive evidence for linkage at 3p14." Mol Psychiatry 11(7): 685-694.
Disease Type Bipolar I Disorder
Study Design pedigree
Study Type Genome-wide linkage study
Sample Size 87 sib-pairs from 70 nuclear families ascertained through an early-onset BPAD type I proband.
SNP/Region/Marker Size 384 microsatellite markers for whole genome wide
Predominant Ethnicity Caucasian
Population European
Gender The sex (male/female) ratio was 0.66 for probands and 0.76 for siblings for the broad phenotype,the sex ratio was 0.80 for probands and 0.87 for siblings for the narrow phenotype.
Age Group For the broad phenotype, mean AAO was 17.2,SD=2.4 years (range 11-21 years) for probands and 22.0,SD=6.8 years (range 9-46 years) for siblings.For the narrow phenotype, mean AAO was 17.4,SD=2.5 years (range 12-21 years) for probands and 17.5,SD= 2.9 years (range 9-21) for siblings.

Detail Info

Regions reported by this study for BD (count: 19)