BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Meta-analysis Report

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Basic Info

Reference	Tang, B.,2011 PMID: 21559500
Citation	Tang, B., T. Thornton-Wells, et al. (2011). "Comparative linkage meta-analysis reveals regionally-distinct, disparate genetic architectures: application to bipolar disorder and schizophrenia." PLoS One 6(4): e19073.
Disease Type	Bipolar Disorder & Schizophrenia
Study Type	Genome-wide linkage study

Detail Info

Regions reported by this study for BD (count: 16)

Region	Statistical Values	Author Comments	Result Category
2p16.1-q11.2	Linkage Meta-Analyses: MSP single P-value = 0.07683, MSP best P-value = 0.01821	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
22q12.3-q13.33	Linkage Meta-Analyses: MSP single P-value = 0.01685, MSP best P-value = 0.01685	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
2p22.2-p13.3	Linkage Meta-Analyses: MSP single P-value = 0.02377, MSP best P-value = 0.00832	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
2p16.2-p11.2	Linkage Meta-Analyses: MSP single P-value = 0.01815, MSP best P-value = 0.00348	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
5p13.3-q13.3	Linkage Meta-Analyses: MSP single P-value = 0.000000363, MSP best P-value = 0.000000363	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
2p25.3-p25.1	Linkage Meta-Analyses: MSP single P-value = 0.00564, MSP best P-value = 0.00268	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
6p23-p21.1	Linkage Meta-Analyses: MSP single P-value = 0.0005, MSP best P-value = 0.00013	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
5q14.3-q23.3	Linkage Meta-Analyses: MSP single P-value = 0.0000000462, MSP best P-value = 0.0000000461	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
8q12.1-q22.1	Linkage Meta-Analyses: MSP single P-value = 0.02829, MSP best P-value = 0.01688	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
8p11.21-q21.13	Linkage Meta-Analyses: MSP single P-value = 0.02212, MSP best P-value = 0.01304	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
8q24.13-q24.3	Linkage Meta-Analyses: MSP single P-value = 0.85627, MSP best P-value = 0.03603	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
10p11.21-q22.1	Linkage Meta-Analyses: MSP single P-value = 0.01274, MSP best P-value = 0.01274	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
10q22.1-q24.1	Linkage Meta-Analyses: MSP single P-value = 0.00389, MSP best P-value = 0.000433	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
14q11.2-q13.1	Linkage Meta-Analyses: MSP single P-value = 0.0000000602, MSP best P-value = 0.0000000602	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
14q12-q22.3	Linkage Meta-Analyses: MSP single P-value = 0.00014, MSP best P-value = 0.00014	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
21q11.2-q21.3	Linkage Meta-Analyses: MSP single P-value = 0.075, MSP best P-value = 0.04112	Significant linkage was found in this region. Significant linkage was found in this region.	Positive