BDgene

SNP Report

Basic Info
Name rs6518291 dbSNP Ensembl
Location chr21:46401674 - 46401674(1)
Variant Alleles A/G
Ancestral Allele G
Minor Allele G
Minor Allele Frequence 0.334665
Functional Annotation missense_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant.
Polyphen Annotation: benign(ENST00000359568)
SIFT Annotation: tolerated(ENST00000359568)
Consequence to Transcript missense_variant(ENST00000359568); non_coding_transcript_exon_variant(ENST00000480896); non_coding_transcript_variant(ENST00000480896)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Anitha, A., 2008 A/G Genotypic P-value = 0.705, allelic P-value = 0.958 for BD wh...... Genotypic P-value = 0.705, allelic P-value = 0.958 for BD when compared with controls. More... none of the SNPs analyzed in our study showed a significant ...... none of the SNPs analyzed in our study showed a significant association with bipolar disorder More... Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
PCNT pericentrin 21q22.3 1(0/1/0)

SNPs in LD with rs6518291 (count: 47) View in gBrowse (chr21:46337878..46599898 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 47)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)