SNP Report

Basic Info

Name	rs3758490 dbSNP Ensembl
Location	chr10:62399574 - 62399574(1)
Variant Alleles	G/T
Ancestral Allele	G
Minor Allele	T
Minor Allele Frequence	0.44389
Functional Annotation	intron_variant; missense_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant. Polyphen Annotation: benign(ENST00000395254) SIFT Annotation: tolerated - low confidence(ENST00000395254)
Consequence to Transcript	intron_variant(ENST00000395255, ENST00000410046); missense_variant(ENST00000395254); non_coding_transcript_exon_variant(ENST00000466727); non_coding_transcript_variant(ENST00000466727)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Anitha, A.,2009	T/G		Fisher's Exact test: Allelic association P-value = 0.445 ; G...... Fisher's Exact test: Allelic association P-value = 0.445 ; Genotypic association P-value = 0.242 More...	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ZNF365	zinc finger protein 365	10q21.2	Mapped by Literature SNP

SNPs in LD with rs3758490 (count: 8) View in gBrowse (chr10:62389722..62427805 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs10995146	intron_variant; non_coding_transcript_variant	0.949[CHB]; 0.804[JPT]
rs3999112	intron_variant	0.949[CHB]; 0.884[CHD]
rs3852425	intron_variant; non_coding_transcript_variant	0.949[CHB]; 0.804[JPT]
rs7904219	intron_variant	0.949[CHB]
rs10821989	intron_variant; non_coding_transcript_variant	0.949[CHB]
rs12779590	intron_variant	0.949[CHB]; 0.911[CHD]; 0.949[JPT]
rs7089814	intron_variant	0.949[CHB]; 0.884[CHD]
rs10995143	intron_variant; non_coding_transcript_variant	0.947[CHB]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)