SNP Report

Basic Info

Name	rs3737438 dbSNP Ensembl
Location	chr21:46391357 - 46391357(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.301518
Functional Annotation	non_coding_transcript_exon_variant; non_coding_transcript_variant; synonymous_variant.
Consequence to Transcript	non_coding_transcript_exon_variant(ENST00000480896); non_coding_transcript_variant(ENST00000480896); synonymous_variant(ENST00000359568)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Anitha, A., 2008	C/T		Genotypic P-value = 0.307, allelic P-value = 0.158 for BD wh...... Genotypic P-value = 0.307, allelic P-value = 0.158 for BD when compared with controls. More...	none of the SNPs analyzed in our study showed a significant ...... none of the SNPs analyzed in our study showed a significant association with bipolar disorder More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PCNT	pericentrin	21q22.3	1(0/1/0)

SNPs in LD with rs3737438 (count: 46) View in gBrowse (chr21:46346736..46544730 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 46)

rs_ID	Functional Annotation	r²[population]
rs2070432	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.864[CHB]; 0.86[JPT]
rs11702704	downstream_gene_variant	0.864[CHB]; 0.86[JPT]
rs2839311	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.955[CHB]; 0.953[JPT]
rs2839241	intron_variant; non_coding_transcript_variant	1.0[CHB]; 0.953[JPT]
rs2073382	intron_variant; non_coding_transcript_variant	1.0[CHB]; 0.953[JPT]
rs3788265	intron_variant; non_coding_transcript_variant	0.866[JPT]
rs11701571	intron_variant; non_coding_transcript_variant	0.866[CHB]; 0.857[JPT]
rs2839314	intron_variant; non_coding_transcript_variant	0.86[CHB]; 0.86[JPT]
rs1007893	upstream_gene_variant	0.955[CHB]; 0.953[JPT]
rs2839217	intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; splice_region_variant; upstream_gene_variant	0.909[CHB]
rs2839304	intron_variant; non_coding_transcript_variant	0.86[CHB]; 0.866[JPT]
rs718496	intron_variant	0.856[CHB]; 0.857[JPT]
rs9306157	intron_variant; non_coding_transcript_variant	0.864[CHB]; 0.86[JPT]
rs2839258	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CHB]; 0.953[JPT]
rs9647245	intron_variant	0.956[CHB]; 0.955[JPT]
rs2839250	intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CHB]; 0.955[JPT]
rs9981212	intron_variant; non_coding_transcript_variant	0.956[CHB]; 0.955[JPT]
rs2839290	intron_variant	0.864[CHB]; 0.953[JPT]
rs6518299	intron_variant; non_coding_transcript_variant	0.951[CHB]; 0.95[JPT]
rs2236616	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CHB]; 0.905[JPT]
rs2839312	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.854[CHB]; 0.846[JPT]
rs4347941	intron_variant; non_coding_transcript_variant	0.955[CHB]; 0.953[JPT]
rs1892691	intron_variant; non_coding_transcript_variant	0.956[CHB]; 1.0[JPT]
rs7277986	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.956[CHB]; 0.95[JPT]
rs8129460	intron_variant; non_coding_transcript_variant	0.911[CHB]; 0.86[JPT]
rs2839306	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.814[JPT]
rs11702701	intron_variant	0.956[CHB]; 0.955[JPT]
rs2839295	intron_variant	0.864[CHB]; 0.86[JPT]
rs2839279	intron_variant	0.955[CHB]; 0.953[JPT]
rs2839269	downstream_gene_variant; intron_variant	0.867[CHB]; 0.821[JPT]
rs2070433	intron_variant; non_coding_transcript_variant	0.864[CHB]; 0.86[JPT]
rs2839288	intron_variant	0.956[CHB]; 0.955[JPT]
rs2070435	non_coding_transcript_exon_variant; non_coding_transcript_variant; synonymous_variant	0.864[CHB]; 0.86[JPT]
rs725970	intron_variant; non_coding_transcript_variant	0.826[CHB]; 0.864[JPT]
rs11702278	intron_variant; non_coding_transcript_variant	0.906[CHB]; 0.954[JPT]
rs7279002	synonymous_variant	0.821[CHB]; 0.86[JPT]
rs721131	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.869[CHB]; 0.866[JPT]
rs1029231	intron_variant; non_coding_transcript_variant	0.864[CHB]; 0.86[JPT]
rs2073379	intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.814[CHB]
rs9647244	intron_variant	0.955[CHB]; 0.953[JPT]
rs2096507	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.953[CHB]; 0.953[JPT]
rs1892692	intron_variant; non_coding_transcript_variant	0.955[CHB]; 0.953[JPT]
rs2839281	intron_variant	0.956[CHB]; 0.955[JPT]
rs6518300	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.956[CHB]; 0.955[JPT]
rs2839278	intron_variant	0.955[CHB]; 0.953[JPT]
rs2839287	intron_variant	0.906[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)