SNP Report

Basic Info
Name rs2279465 dbSNP Ensembl
Location chr11:46377988 - 46377988(1)
Variant Alleles T/C
Ancestral Allele C
Minor Allele C
Minor Allele Frequence 0.211262
Functional Annotation downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000524869, ENST00000529698, ENST00000577966); intron_variant(ENST00000318201, ENST00000343674, ENST00000421244, ENST00000454345, ENST00000456247, ENST00000524984, ENST00000527911, ENST00000528173, ENST00000528615, ENST00000529660, ENST00000531879, ENST00000532868); NMD_transcript_variant(ENST00000524984); non_coding_transcript_exon_variant(ENST00000527211, ENST00000532941, ENST00000534802); non_coding_transcript_variant(ENST00000527211, ENST00000528173, ENST00000529660, ENST00000531879, ENST00000532941, ENST00000534802); upstream_gene_variant(ENST00000359803, ENST00000395565, ENST00000395566, ENST00000395569, ENST00000405308, ENST00000407067, ENST00000441869, ENST00000481047, ENST00000489525, ENST00000490240, ENST00000533283, ENST00000533952, ENST00000617138)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Shi, J., 2007 A/G TDT P-value = 0.15 of Allelic Association With Bipolar Disor...... TDT P-value = 0.15 of Allelic Association With Bipolar Disorder in the Combined Sample More... Negative

SNP related genes (count: 4)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
MIR4688 microRNA 4688 11 Mapped by Literature SNP
DGKZ diacylglycerol kinase, zeta 11p11.2 Mapped by Literature SNP
MDK midkine (neurite growth-promoting factor 2) 11p11.2 Mapped by Literature SNP
CHRM4 cholinergic receptor, muscarinic 4 11p12-p11.2 1(0/1/0)

SNPs in LD with rs2279465 (count: 35) View in gBrowse (chr11:46349217..46575124 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 35)

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)