SNP Report

Basic Info

Name	rs2015181 dbSNP Ensembl
Location	chr22:34708064 - 34708064(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.369409
Functional Annotation	downstream_gene_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000440858); upstream_gene_variant(ENST00000423712)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Potash, J. B., 2008	A/G		Family-based P-value = 0.16 for all BPAD subjects, family-ba...... Family-based P-value = 0.16 for all BPAD subjects, family-based P-value = 0.3 for BPAD subjects with psychotic symptoms, family-based P-value = 0.15 (3-marker sliding window with indicated marker first of the three), family-based P-value = 0.18 (3-marker sliding window with indicated marker first of the three using only those BPAD subjects with psychotic symptoms).Case-control P-value = 0.49 for all BPAD subjects, case-control P-value = 0.24 for BPAD subjects with psychotic symptoms, case-control P-value = 0.45 (3-marker sliding window with indicated marker first of the three), case-control P-value = 0.21 (3-marker sliding window with indicated marker first of the three using only those BPAD subjects with psychotic symptoms). More...		Negative

SNP related genes (count: 0)

SNPs in LD with rs2015181 (count: 62) View in gBrowse (chr22:34590408..34742130 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 62)

rs_ID	Functional Annotation	r²[population]
rs4552280		0.858[CEU]
rs974223		0.813[CEU]
rs4821290	intron_variant; non_coding_transcript_variant	0.951[CEU]
rs11089689		0.948[CEU]
rs1573683	non_coding_transcript_exon_variant; non_coding_transcript_variant	1.0[CEU]
rs1123411		0.806[CEU]
rs2071713	downstream_gene_variant	1.0[CEU]
rs5755201		1.0[CEU]
rs714029		1.0[CEU]
rs713820		1.0[CEU]; 1.0[TSI]
rs2227076		1.0[CEU]
rs2213448		0.813[CEU]; 0.878[TSI]
rs5755261		1.0[CEU]
rs5755246	upstream_gene_variant	1.0[CEU]
rs2413259	upstream_gene_variant	1.0[CEU]
rs9610076		0.843[CEU]
rs2205811		0.813[CEU]; 0.878[TSI]
rs4821281		0.813[CEU]; 0.878[TSI]
rs2413262	upstream_gene_variant	1.0[CEU]; 0.95[TSI]
rs728308		0.813[CEU]
rs4821279		0.813[CEU]
rs9607169		1.0[CEU]
rs972716		1.0[CEU]
rs713632	upstream_gene_variant	1.0[CEU]
rs5755252		1.0[CEU]
rs1547414		1.0[CEU]; 1.0[TSI]
rs5755184	non_coding_transcript_exon_variant; non_coding_transcript_variant	0.861[TSI]
rs9610075		1.0[CEU]; 1.0[TSI]
rs7291061		0.813[CEU]; 0.878[TSI]
rs2071714	downstream_gene_variant	0.802[CEU]; 0.878[TSI]
rs2006781		1.0[CEU]
rs7286170		0.813[CEU]; 0.878[TSI]
rs909566	downstream_gene_variant	0.861[TSI]
rs5749920	downstream_gene_variant	0.861[TSI]
rs4821268		0.861[TSI]
rs4820157		0.813[CEU]
rs2413258	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs7289548		0.828[CEU]
rs737761	intron_variant; non_coding_transcript_variant; splice_region_variant	1.0[CEU]
rs2227074		0.813[CEU]
rs4821284		1.0[CEU]; 1.0[TSI]
rs5755259		1.0[CEU]; 1.0[TSI]
rs2413257	non_coding_transcript_exon_variant; non_coding_transcript_variant	1.0[CEU]
rs1010035	intron_variant; non_coding_transcript_variant	0.813[CEU]
rs2071712	downstream_gene_variant	1.0[CEU]
rs4821282		0.813[CEU]
rs4821287		0.813[CEU]
rs9610078		1.0[CEU]
rs2413255		0.813[CEU]; 0.878[TSI]
rs9610097	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs967917		1.0[CEU]; 1.0[TSI]
rs5749922		0.861[TSI]
rs2205810		0.861[TSI]
rs5755202		0.813[CEU]; 0.878[TSI]
rs974224		0.808[CEU]
rs874814	non_coding_transcript_exon_variant; non_coding_transcript_variant	0.84[TSI]
rs4821280		0.813[CEU]
rs5749925		0.813[CEU]
rs4630867		1.0[CEU]
rs9607167		0.861[TSI]
rs5755241	intron_variant; non_coding_transcript_variant	0.908[CEU]; 0.951[TSI]
rs2413253		0.813[CEU]; 0.878[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)