SNP Report

Basic Info

Name	rs1416325 dbSNP Ensembl
Location	chr9:76140576 - 76140576(1)
Variant Alleles	G/T
Ancestral Allele	G
Minor Allele	T
Minor Allele Frequence	0.282947
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000376752, ENST00000376767, ENST00000424854, ENST00000545128)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Hattori, E.,2009			In GWAS: Allelic P-value = 0.00824, Genotypic P-value = 0.03...... In GWAS: Allelic P-value = 0.00824, Genotypic P-value = 0.03772, Recessive P-value = 0.02484, HWE P-value = 0.22884; in Follow-up study: MAF=0.28, Allelic P-value = 0.03521, Allelic Q-value=0.54802, HWE P-value = 0.99691 More...	Significant association was observed in both GWAS and Follow...... Significant association was observed in both GWAS and Follow-up study. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PCSK5	proprotein convertase subtilisin/kexin type 5	9q21.13	1(1/0/0)

SNPs in LD with rs1416325 (count: 3) View in gBrowse (chr9:76136716..76142251 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs6560506	intron_variant	0.95[CHB]; 1.0[JPT]
rs4745507	intron_variant	0.848[CHB]
rs11144764	intron_variant	1.0[CHB]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)