SNP Report

Basic Info

Name	rs12539777 dbSNP Ensembl
Location	chr7:103420252 - 103420252(1)
Variant Alleles	G/A
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.214058
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000306312, ENST00000339444, ENST00000354356, ENST00000356767, ENST00000393723, ENST00000393727, ENST00000393729, ENST00000393730, ENST00000393735, ENST00000423416, ENST00000432958, ENST00000445809, ENST00000454864, ENST00000456463, ENST00000487407); NMD_transcript_variant(ENST00000423416, ENST00000445809, ENST00000454864, ENST00000456463); non_coding_transcript_variant(ENST00000487407)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Chen, X., 2015	A/G		P-value=9.25E-24,Â OR=2.74, 95%CI=2.24-3.34 P-value=9.25E-24,Â OR=2.74, 95%CI=2.24-3.34	Chromosome 7 associated SNPs and flanking genes for bipolar ...... Chromosome 7 associated SNPs and flanking genes for bipolar disorder (BPD) from Affymetrix Genome-wide Human SNP Array 6.0 in the population of Shandong province of China. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SLC26A5	solute carrier family 26 (anion exchanger), member 5	7q22	Mapped by Literature SNP

SNPs in LD with rs12539777 (count: 3) View in gBrowse (chr7:103419880..103491048 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs12532364	intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	0.901[CHD]
rs6955482	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs971846	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.818[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)