BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Region Report

Basic Info

Region Name	21q21
Chromosome Position	chr21:15000000-30200000
No. of Studies (Positive/Negative/Trend)	2(1/0/1)

Region related studies (count: 2)

Reference	Markers	Statistical Values	Author Comments	Result Category
Cassidy, F.,2007	D21S1437	Pairwise Linkage Analysis: narrow model, NPL = 1.95952, P-va...... Pairwise Linkage Analysis: narrow model, NPL = 1.95952, P-value = 0.026101; Multipoint Linkage Analysis: narrow model, NPL = 1.90954, P-value = 0.029272; Pairwise Linkage Analysis: Broad model, NPL = 1.37995, P-value = 0.084357; Structure-Guided Linkage Analysis: Broad model: NPL = 1.63, P-value = 0.05 for all families.; NPL = 1.12, P-value = 0.13 for families.; Narrow model: NPL = 1.99, P-value = 0.024 for all families.; NPL = 1.47, P_value = 0.072 for 60% homogeneous families. More...	There is a trend for Significant linkage. There is a trend for Significant linkage.	Trend
Fullerton, J. M.,2008	D21S1256	Linkage analysis: LOD = 3.45, 90rec model Linkage analysis: LOD = 3.45, 90rec model	Significant linkage was found in this region. Significant linkage was found in this region.	Positive

Region related genes (count: 0)

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Region: chr21:15000000..30200000 View in gBrowse