Gene Report

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Basic Info

Approved Symbol	FAM110B
Previous Symbol	C8orf72
Symbol Alias	MGC39325
Approved Name	family with sequence similarity 110, member B
Previous Name	chromosome 8 open reading frame 72
Location	8q12.1
Position	chr8:57994509-58204279, 1
External Links	HGNC: 28587 Entrez Gene: 90362 Ensembl: ENSG00000169122 UCSC: uc003xtj.1
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Johnson, C.,2009		Monte-Carlo Simulation P-value = 0.0002. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 3)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005815	microtubule organizing center	cellular component	IEA	10
GO:0005737	cytoplasm	cellular component	IDA	322
GO:0005739	mitochondrion	cellular component	IDA	75

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
8q12.1-q22.1	chr8:54600000-97900000	1 (1/0/0)
8p11.21-q21.13	chr8:39900000-83500000	1 (1/0/0)
Chr 8	chr8:0-145138636	3 (0/3/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr8:57994509..58204279 View in gBrowse