BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Other Variant Report

Basic Info

Name	NRG1 D8S1810
Type	microsatellite
Related Gene	NRG1
No. of Study	1 (Positive: 1; Negative 0; Trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Variant related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Cassidy, F., 2006	1-8 allele		TDT P-value = 0.19, X²=1.7 for 2 allele; TDT P-value = 0.26, X²=1.29 for 4 allele; TDT P-value = 0.04, X²=4.05 for 5 allele; TDT P-value = 0.62, X²=0.25 for 6 allele; TDT P-value = 0.84, X²=0.04 for 8 allele; Global P-value = 0.21, Globala X²=9.62, df=7	From the single marker association analysis, there was no ev..... More From the single marker association analysis, there was no evidence of association of NRG1 with BPAD in this sample. D8S1810 did exhibit a significant over transmission of allele 5 to bipolar probands (uncorrected P=0.04) but the global P-value for this marker was not significant (P=0.212). Less	Positive

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)