BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Study Report

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Basic Info

Reference	Schirmbeck, F., 2007 PMID: 17413456
Citation	Schirmbeck, F., A. Georgi, et al. (2007). "No association between the serine racemase gene (SRR) and bipolar disorder in a German case-control sample." Psychiatr Genet 17(2): 127.
Disease Type	Bipolar Disorder
Study Design	case-control
Study Type	Candidate-gene association study
Sample Size	180 patients and 289 population-based controls
SNP/Region/Marker Size	3 SNPs
Predominant Ethnicity	Caucasian
Population	Germany
Gender	BD patients: 45% men and 55% women; controls: 40% men and 60% women
Age Group	adults : mean age=42 (SD=13.3) years of patients, mean age=49 (SD=15.4) years of controls

Detail Info

SNPs reported by this study for BD (count: 3)

SNP	Related Gene(s)	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
rs391300	SRR	C/T		no P-value given in the orignial article	allele and haplotype frequencies did not differ between case...... allele and haplotype frequencies did not differ between cases and controls More...	Negative
rs721629	PSD3 SRR	G/T		no P-value given in the orignial article	allele and haplotype frequencies did not differ between case...... allele and haplotype frequencies did not differ between cases and controls More...	Negative
rs8081273	TSR1 SRR	C/T		no P-value given in the orignial article	allele and haplotype frequencies did not differ between case...... allele and haplotype frequencies did not differ between cases and controls More...	Negative

Genes reported by this study for BD (count: 1)