SNP Report

Basic Info

Name	rs9436299 dbSNP Ensembl
Location	chr1:65427205 - 65427205(1)
Variant Alleles	C/A
Ancestral Allele	A
Minor Allele	C
Minor Allele Frequence	0.358626
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000349533, ENST00000371059, ENST00000371060, ENST00000371065, ENST00000406510, ENST00000475108, ENST00000484243, ENST00000488747, ENST00000497874, ENST00000613538, LRG_283t1, LRG_283t2, LRG_283t3); non_coding_transcript_variant(ENST00000475108, ENST00000484243, ENST00000488747, ENST00000497874)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Gratacos, M.,2009			Single SNP association: In control and bipolar disorder samp...... Single SNP association: In control and bipolar disorder samples: Dominant Model, P-value = 0.0125(corrected by genomic control, Reus), P-value = 0.0464(passed multiple testing correction, Madrid); OR(95% CI): Reus: 1.56 (1.13-2.15), Madrid: 1.43 (1.00-2.05) More...	Nominal statistical significance was observed as P-value < 0...... Nominal statistical significance was observed as P-value < 0.05 using both control sets under the same genotypic mode. More...	Positive

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
LEPROT	leptin receptor overlapping transcript	1p31.2	Mapped by Literature SNP
LEPR	leptin receptor	1p31	1(1/0/0)

SNPs in LD with rs9436299 (count: 22) View in gBrowse (chr1:65427205..65517574 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs1327116	intron_variant	0.838[CEU]
rs6588147	intron_variant	0.844[CEU]; 0.89[TSI]
rs1327121	intron_variant; non_coding_transcript_variant	0.844[CEU]; 0.859[TSI]
rs1171274	intron_variant	0.845[CEU]
rs10889556	intron_variant	0.845[CEU]
rs2025804	intron_variant	0.844[CEU]; 0.86[TSI]
rs1475398	intron_variant	0.808[CEU]
rs9436747	intron_variant	0.844[CEU]
rs4655811	intron_variant	0.922[CEU]
rs10889557	intron_variant	0.807[CEU]
rs9436300	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.841[CEU]
rs2104564	intron_variant	0.845[CEU]
rs7534511	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.839[CEU]
rs10889558	intron_variant	0.845[CEU]
rs6657868	intron_variant	0.844[CEU]
rs7555955	intron_variant	0.839[CEU]
rs11208654	intron_variant	0.844[CEU]; 0.832[TSI]
rs12068561	intron_variant	0.839[CEU]
rs1046011	3_prime_UTR_variant; downstream_gene_variant; intron_variant	0.921[CEU]
rs970468	downstream_gene_variant; intron_variant	0.844[CEU]
rs7533108	intron_variant	0.833[CEU]
rs7516840	intron_variant	0.837[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)