SNP Report

Basic Info

Name	rs9378249 dbSNP Ensembl
Location	chrCHR_HSCHR6_MHC_SSTO_CTG1:31353627 - 31353627(1)
Variant Alleles	T/G
Minor Allele	G
Minor Allele Frequence	0.0686901
Functional Annotation	downstream_gene_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000603274); upstream_gene_variant(ENST00000412585, ENST00000434333, ENST00000463574, ENST00000474381, ENST00000497377, ENST00000498007, ENST00000618788, ENST00000416726, ENST00000425848, ENST00000445222, ENST00000461583, ENST00000470915, ENST00000473379, ENST00000490676, ENST00000430299, ENST00000435618, ENST00000436729, ENST00000465455, ENST00000481283, ENST00000488367, ENST00000489762, ENST00000425798, ENST00000437866, ENST00000450871, ENST00000462100, ENST00000469883, ENST00000471639, ENST00000494335, ENST00000359635, ENST00000418147, ENST00000466304, ENST00000475493, ENST00000479203, ENST00000479990, ENST00000493512, ENST00000421349, ENST00000437265, ENST00000445610, ENST00000463600, ENST00000463832, ENST00000475902, ENST00000498484)
No. of Studies	2 (Positive: 1; Negative: 0; Trend: 1)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Ross, K. A.,2011	T/G		Using the stringent filter, two-sided chi-squared test, geno...... Using the stringent filter, two-sided chi-squared test, genotype P-value = 0.00000005 More...	Suggestive association was found. Suggestive association was found.	Trend
Jiang, Y.,2011			Non-weighted test under H0: P-value(additive)=0.0000000121, ...... Non-weighted test under H0: P-value(additive)=0.0000000121, P-value(dominant)=0.0000000511, P-value(recessive)=0.00506; weighted test under H'0: P-value(additive)=0.0000000139, P-value(dominant)=0.0000000341, P-value(recessive)=0.00755; logistic regression: P-value(additive)=0.00000000171, P-value(dominant)=0.0000000077, P-value(recessive)=0.000887 More...	Significant associations were found . Significant associations were found .	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
HLA-B	major histocompatibility complex, class I, B	6p21.3	2(0/1/1)

SNPs in LD with rs9378249 (count: 0) View in gBrowse (chrCHR_HSCHR6_MHC_SSTO_CTG1:31353627..31353627 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)