SNP Report

Basic Info

Name	rs933305 dbSNP Ensembl
Location	chr12:111300483 - 111300483(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.487021
Functional Annotation	intron_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000261726); upstream_gene_variant(ENST00000617342)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Glaser, B.,2005(b)	T/C		For Sample I+II, allelic association: X²=5.32, P-...... For Sample I+II, allelic association: X²=5.32, P-value = 0.02, OR(95%CI)=0.7(0.6-10); genotypic association: X²=5.4, P-value = 0.07 More...	Significant association was observed in allelic association. Significant association was observed in allelic association.	Positive
Yosifova, A.,2009	A/G		Allelic association: P-value = 0.24 Allelic association: P-value = 0.24	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CUX2	cut-like homeobox 2	12q24.12	3(1/2/0)

SNPs in LD with rs933305 (count: 2) View in gBrowse (chr12:111300483..111304418 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs1362006		downstream_gene_variant; intron_variant	0.809[CEU]
rs10849930		intron_variant; upstream_gene_variant	0.831[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)