BDgene

SNP Report

Basic Info
Name rs875326 dbSNP Ensembl
Location chr1:175320263 - 175320263(1)
Variant Alleles C/T
Ancestral Allele T
Minor Allele T
Minor Allele Frequence 0.211861
Functional Annotation 3_prime_UTR_variant; downstream_gene_variant; intron_variant; non_coding_transcript_variant.
Consequence to Transcript 3_prime_UTR_variant(ENST00000367674); downstream_gene_variant(ENST00000263525); intron_variant(ENST00000569593); non_coding_transcript_variant(ENST00000569593)
No. of Studies 2 (Positive: 0; Negative: 2; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Green, E. K.,2012 C/T BD ImmunoChip:P-value = 0.378,OR = 0.945;ImmunoChip, PGC-BD ...... BD ImmunoChip:P-value = 0.378,OR = 0.945;ImmunoChip, PGC-BD combined data:P-balue = 0.00105,OR = 1.078 More... No significant association was observed. No significant association was observed. Negative
Sklar, P.,2011 C/T Primary GWAS P-value(GC)=0.0000251, OR=1.15; replication P-v...... Primary GWAS P-value(GC)=0.0000251, OR=1.15; replication P-value(1-sided)=0.183, OR=1.03; Combined GWAS and replication P-value(GC)=0.000111, OR=1.1 More... No significant association was observed. No significant association was observed. Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
TNR tenascin R 1q24 2(0/2/0)

SNPs in LD with rs875326 (count: 6) View in gBrowse (chr1:175320200..175340145 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 6)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)