BDgene

SNP Report

Basic Info
Name rs7917983 dbSNP Ensembl
Location chr10:112973123 - 112973123(1)
Variant Alleles T/C
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.371206
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000346198, ENST00000352065, ENST00000355717, ENST00000355995, ENST00000369395, ENST00000369397, ENST00000534894, ENST00000536810, ENST00000538897, ENST00000542695, ENST00000543371, ENST00000545257, ENST00000627217, ENST00000629706)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Cuellar-Barboza, A. B., 2016 G SNP main effect: P-value=0.87, OR=1.01; SNP-BMI interaction...... SNP main effect: P-value=0.87, OR=1.01; SNP-BMI interaction: P-value=0.021, OR=1.03 More... Seven out of the 26 genotyped TCF7L2 SNPs showed a significa...... Seven out of the 26 genotyped TCF7L2 SNPs showed a significant SNP–BMI interaction effect, with p < 0.05. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 10q25.3 1(1/0/0)

SNPs in LD with rs7917983 (count: 1) View in gBrowse (chr10:112973123..112973147 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 1)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)