BDgene

SNP Report

Basic Info
Name rs7757037 dbSNP Ensembl
Location chr6:35580459 - 35580459(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele A
Minor Allele Frequence 0.472644
Functional Annotation downstream_gene_variant; intron_variant.
Consequence to Transcript downstream_gene_variant(ENST00000542713); intron_variant(ENST00000357266, ENST00000536438, ENST00000539068)
No. of Studies 2 (Positive: 1; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Willour, V. L.,2009 G/A FBAT: Additive model: major allele P-value = 0.005, minor al...... FBAT: Additive model: major allele P-value = 0.005, minor allele P-value = 0.005; Dominant model: major allele P-value = 0.310, minor allele P-value = 0.001; Genotypic association: TDT P-value = 0.007 More... It showed a significant overtransmission under the dominant ...... It showed a significant overtransmission under the dominant model and a significant association in TDT result. More... Positive
Ceulemans, S.,2011 A/G Single SNP analyses: Permuted P-value = 0.2244, Odds Ratio=1...... Single SNP analyses: Permuted P-value = 0.2244, Odds Ratio=1.153 More... No significant association was observed. No significant association was observed. Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
FKBP5 FK506 binding protein 5 6p21.31 5(1/4/0)

SNPs in LD with rs7757037 (count: 0) View in gBrowse (chr6:35580459..35580459 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)