BDgene

SNP Report

Basic Info
Name rs7645772 dbSNP Ensembl
Location chr3:129976530 - 129976530(1)
Variant Alleles T/C
Ancestral Allele T
Minor Allele C
Minor Allele Frequence 0.272165
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000302649, ENST00000507066)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Gratacos, M.,2009 Single SNP association: In control and bipolar disorder samp...... Single SNP association: In control and bipolar disorder samples: Dominant Model, P-value = 0.0157(corrected by genomic control, Reus), P-value = 0.04997(passed multiple testing correction, Madrid); OR(95% CI): Reus: 1.62 (1.12-2.36), Madrid: 1.49 (1.00-2.24) More... Nominal statistical significance was observed as P-value < 0...... Nominal statistical significance was observed as P-value < 0.05 using both control sets under the same genotypic mode. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
TRH thyrotropin-releasing hormone 3q13.3-q21 1(1/0/0)

SNPs in LD with rs7645772 (count: 10) View in gBrowse (chr3:129968972..129996953 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 10)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)