SNP Report

Basic Info

Name	rs743810 dbSNP Ensembl
Location	chr22:35346932 - 35346932(1)
Variant Alleles	T/G
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.350839
Functional Annotation	3_prime_UTR_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; splice_region_variant; synonymous_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000404284, ENST00000424387); intron_variant(ENST00000382034); NMD_transcript_variant(ENST00000404284, ENST00000424387); non_coding_transcript_exon_variant(ENST00000492723); non_coding_transcript_variant(ENST00000492723); splice_region_variant(ENST00000404284, ENST00000411850, ENST00000424387, ENST00000425375, ENST00000447733, ENST00000449058, ENST00000492723); synonymous_variant(ENST00000411850, ENST00000425375, ENST00000447733, ENST00000449058)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Potash, J. B., 2008	A/C		Family-based P-value = 0.42 for all BPAD subjects, family-ba...... Family-based P-value = 0.42 for all BPAD subjects, family-based P-value = 0.43 for BPAD subjects with psychotic symptoms, family-based P-value = 0.047 (3-marker sliding window with indicated marker first of the three), family-based P-value = 0.12 (3-marker sliding window with indicated marker first of the three using only those BPAD subjects with psychotic symptoms).Case-control P-value = 0.91 for all BPAD subjects, case-control P-value = 0.74 for BPAD subjects with psychotic symptoms, case-control P-value = 0.32 (3-marker sliding window with indicated marker first of the three), case-control P-value = 0.25 (3-marker sliding window with indicated marker first of the three using only those BPAD subjects with psychotic symptoms). More...		Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TOM1	target of myb1 (chicken)	22q13.1	1(1/0/0)

SNPs in LD with rs743810 (count: 2) View in gBrowse (chr22:35346932..35349531 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs5750101		downstream_gene_variant	0.817[CEU]
rs6518950		downstream_gene_variant	0.816[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)