SNP Report

Basic Info

Name	rs7301328 dbSNP Ensembl
Location	chr12:13865843 - 13865843(1)
Variant Alleles	G/C/T
Ancestral Allele	G
Minor Allele	C
Minor Allele Frequence	0.441494
Functional Annotation	downstream_gene_variant; synonymous_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000627535, ENST00000630791); synonymous_variant(ENST00000609686)
No. of Studies	2 (Positive: 0; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Zhao, Q.,2011	C/G		X² test: allele, OR(95%CI)=1.13(0.94-1.35), X X² test: allele, OR(95%CI)=1.13(0.94-1.35), X²=1.677, P-value = 0.195, genotype, X²=2.096, P-value = 0.351 More...	No significant association was observed in BD. No significant association was observed in BD.	Negative
Yosifova, A.,2009	G/C		Allelic association: P-value = 0.73 Allelic association: P-value = 0.73	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	12p13.1	8(4/4/0)

SNPs in LD with rs7301328 (count: 3) View in gBrowse (chr12:13865843..13878511 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs12582848	intron_variant	1.0[CHB]; 0.81[JPT]
rs10845847	intron_variant	0.821[JPT]
rs10845851	intron_variant	0.825[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)