SNP Report

Basic Info

Name	rs6982890 dbSNP Ensembl
Location	chr8:32757580 - 32757580(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.178315
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000518084, ENST00000519240, ENST00000522402, ENST00000522569); intron_variant(ENST00000287842, ENST00000356819, ENST00000405005, ENST00000518104, ENST00000519301, ENST00000521670, ENST00000523079, ENST00000523534, ENST00000539990)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Cao L., 2014	A/G		Total BPI vs. controls: X²=0.04, OR=0.98, 95%CI=0...... Total BPI vs. controls: X²=0.04, OR=0.98, 95%CI=0.77-1.25, Bonf P-value=1; BPI-P vs. controls: X²=0.14, OR=0.95, 95%CI=0.72-1.25, Bonf P-value=1; BPI-NP vs. controls: X²=0, OR=1, 95%CI=0.68-1.48, Bonf P-value=1 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NRG1	neuregulin 1	8p12	15(10/5/0)

SNPs in LD with rs6982890 (count: 2) View in gBrowse (chr8:32757580..32767310 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs6992642		3_prime_UTR_variant; downstream_gene_variant	0.846[CHB]
rs3735781		3_prime_UTR_variant; downstream_gene_variant	1.0[CHB]; 0.922[CHD]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)