BDgene

SNP Report

Basic Info
Name rs684513 dbSNP Ensembl
Location chr15:78566058 - 78566058(1)
Variant Alleles C/G
Ancestral Allele C
Minor Allele G
Minor Allele Frequence 0.289337
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000299565, ENST00000559554)
No. of Studies 2 (Positive: 0; Negative: 2; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Hartz, S. M.,2011 X2 test: for nicotine dependence with and without...... X2 test: for nicotine dependence with and without bipolar disorder, allele P-value = 0.36; logistic regression: for BD case-control, P-value = 0.19, OR=0.9, 95% CI=0.8-1.1, when smoking as a covariate, P-value = 0.22, OR=0.9, for non-smokers only, P-value = 0.43, OR=0.91 More... No significant association was observed. No significant association was observed. Negative
Shi, J., 2007 C/G TDT P-value = 0.25 of Allelic Association With Bipolar Disor...... TDT P-value = 0.25 of Allelic Association With Bipolar Disorder in the Combined Sample More... Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 15q24 3(2/1/0)

SNPs in LD with rs684513 (count: 10) View in gBrowse (chr15:78420357..78580777 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 10)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016