SNP Report

Basic Info

Name	rs6732758 dbSNP Ensembl
Location	chr2:174745231 - 174745231(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.266973
Functional Annotation	downstream_gene_variant; intron_variant; non_coding_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000261007, ENST00000348749, ENST00000409219, ENST00000409542, ENST00000435083, ENST00000636168); intron_variant(ENST00000442996); non_coding_transcript_variant(ENST00000442996)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Shi, J., 2007	A/G		TDT P-value = 0.32 of Allelic Association With Bipolar Disor...... TDT P-value = 0.32 of Allelic Association With Bipolar Disorder in the Combined Sample More...		Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CHRNA1	cholinergic receptor, nicotinic, alpha 1 (muscle)	2q31.1	2(0/1/1)

SNPs in LD with rs6732758 (count: 5) View in gBrowse (chr2:174745231..174765747 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs2600683	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.815[TSI]
rs1530906	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.815[TSI]
rs12997022	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.85[TSI]
rs2646165	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.81[TSI]
rs1376865	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.808[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)