SNP Report

Basic Info

Name	rs637137 dbSNP Ensembl
Location	chr15:78581634 - 78581634(1)
Variant Alleles	T/A
Ancestral Allele	T
Minor Allele	A
Minor Allele Frequence	0.39976
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000299565, ENST00000394802, ENST00000559554)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Hartz, S. M.,2011			X² test: for nicotine dependence with and without...... X² test: for nicotine dependence with and without bipolar disorder, allele P-value = 0.19; logistic regression: for BD case-control, P-value = 0.11, OR=0.88, 95% CI=0.7-1.0, when smoking as a covariate, P-value = 0.13, OR=0.88, for non-smokers only, P-value = 0.43, OR=0.91 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CHRNA5	cholinergic receptor, nicotinic, alpha 5 (neuronal)	15q24	3(2/1/0)

SNPs in LD with rs637137 (count: 0) View in gBrowse (chr15:78581634..78581634 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)