SNP Report

Basic Info

Name	rs6350 dbSNP Ensembl
Location	chrCHR_HSCHR5_3_CTG1:1384987 - 1384987(-1)
Variant Alleles	A/C/G
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.0455272
Functional Annotation	missense_variant; synonymous_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant. Polyphen Annotation: probably damaging(ENST00000270349) SIFT Annotation: tolerated(ENST00000270349)
Consequence to Transcript	missense_variant(ENST00000270349); synonymous_variant(ENST00000270349); non_coding_transcript_exon_variant(ENST00000630039); non_coding_transcript_variant(ENST00000630039); upstream_gene_variant(ENST00000629718, ENST00000630461)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Mick, E., 2008		A	TDT X²(df=1)=1, P-value = 0.412, OR (95% CI)=1.33...... TDT X²(df=1)=1, P-value = 0.412, OR (95% CI)=1.33(0.72-2.46) More...		Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SLC6A3	solute carrier family 6 (neurotransmitter transporter), member 3	5p15.3	11(5/6/0)

SNPs in LD with rs6350 (count: 1) View in gBrowse (chrCHR_HSCHR5_3_CTG1:1384424..1384987 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs11564757		intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]; 0.834[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)