SNP Report

Basic Info

Name	rs600674 dbSNP Ensembl
Location	chr1:84235568 - 84235568(1)
Variant Alleles	T/C
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.211062
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000370682, ENST00000370685, ENST00000370689, ENST00000394838, ENST00000394839, ENST00000610457, ENST00000610703, ENST00000614872); downstream_gene_variant(ENST00000446538)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
McDonald, M. L.,2012			chi square test:OR(95%CI) = 0.8(0.7â€“0.9),P-value = 0.0065 ...... chi square test:OR(95%CI) = 0.8(0.7â€“0.9),P-value = 0.0065 for BD-I More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	1p36.1	1(0/1/0)

SNPs in LD with rs600674 (count: 9) View in gBrowse (chr1:84228559..84263451 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs634904		0.887[CEU]
rs12047850		0.887[CEU]
rs17365096		1.0[CEU]
rs677124		0.887[CEU]
rs615468		1.0[CEU]
rs1027694	downstream_gene_variant; upstream_gene_variant	1.0[CEU]
rs2389717	intron_variant	1.0[CEU]; 1.0[TSI]
rs583720		0.881[CEU]; 0.806[TSI]
rs12406360	downstream_gene_variant	1.0[CEU]; 0.902[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)