SNP Report

Basic Info

Name	rs4923463 dbSNP Ensembl
Location	chr11:27650953 - 27650953(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.230032
Functional Annotation	downstream_gene_variant; intron_variant; non_coding_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000314915, ENST00000356660, ENST00000395978, ENST00000395980, ENST00000395981, ENST00000395983, ENST00000395986, ENST00000418212, ENST00000420794, ENST00000438929, ENST00000439476, ENST00000525528, ENST00000525950, ENST00000530786, ENST00000530861, ENST00000532997, ENST00000533131, ENST00000533246, ENST00000584049); intron_variant(ENST00000499008, ENST00000499568, ENST00000500662, ENST00000501176, ENST00000502161, ENST00000530313, ENST00000530686, ENST00000532965); non_coding_transcript_variant(ENST00000499008, ENST00000499568, ENST00000500662, ENST00000501176, ENST00000502161, ENST00000530313, ENST00000530686, ENST00000532965)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Yosifova, A.,2009	A/G		Allelic association: P-value = 0.015 Allelic association: P-value = 0.015	Significant association was observed Significant association was observed	Positive
Neves, F. S.,2011	G/A		chi-square test: allele, P-value = 0.52, OR(95%CI)=1.14(0.75...... chi-square test: allele, P-value = 0.52, OR(95%CI)=1.14(0.75-1.74), genotype, P-value = 0.691 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
BDNF	brain-derived neurotrophic factor	11p14.1	37(24/12/1)
BDNF-AS	BDNF antisense RNA	11p14.1	Mapped by Literature SNP

SNPs in LD with rs4923463 (count: 0) View in gBrowse (chr11:27650953..27650953 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)