SNP Report

Basic Info

Name	rs4869843 dbSNP Ensembl
Location	chr6:155086849 - 155086849(1)
Variant Alleles	C/T
Ancestral Allele	T
Minor Allele	T
Minor Allele Frequence	0.0321486
Functional Annotation	intron_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000431620, ENST00000461783, ENST00000528535, ENST00000535231, ENST00000538270, ENST00000545347); non_coding_transcript_variant(ENST00000431620); upstream_gene_variant(ENST00000318981)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Hattori, E.,2009			In GWAS: Allelic P-value = 0.00825, Genotypic P-value = 0.03...... In GWAS: Allelic P-value = 0.00825, Genotypic P-value = 0.03325, Recessive P-value = 0.01386, HWE P-value = 0.00243; in Follow-up study: MAF=0.07, Allelic P-value = 0.00755, Allelic Q-value=0.49274, HWE P-value = 0.86312 More...	Significant association was observed in both GWAS and Follow...... Significant association was observed in both GWAS and Follow-up study. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TIAM2	T-cell lymphoma invasion and metastasis 2	6q25	1(1/0/0)

SNPs in LD with rs4869843 (count: 7) View in gBrowse (chr6:155063306..155099557 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs6915661	downstream_gene_variant; intron_variant	1.0[CHB]; 1.0[JPT]
rs17085907	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[JPT]
rs12661761	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[JPT]
rs10223883	intron_variant	0.864[JPT]
rs17798743	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[JPT]
rs13202771	intron_variant	1.0[CHB]; 1.0[JPT]
rs4870347	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)