SNP Report

Basic Info

Name	rs4616318 dbSNP Ensembl
Location	chrCHR_HSCHR17_2_CTG5:45863062 - 45863062(1)
Variant Alleles	A/G
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.352636
Functional Annotation	downstream_gene_variant; intron_variant; non_coding_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000329196); intron_variant(ENST00000579244, ENST00000579599, ENST00000634876); non_coding_transcript_variant(ENST00000579244, ENST00000579599, ENST00000634876, ENST00000610319, ENST00000628274, ENST00000629948, ENST00000628274, ENST00000629948, ENST00000621383, ENST00000632082, ENST00000633517, ENST00000632082, ENST00000633517)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Ceulemans, S.,2011	G/A		Single SNP analyses: Permuted P-value = 0.6243, Odds Ratio=1...... Single SNP analyses: Permuted P-value = 0.6243, Odds Ratio=1.062 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
MAPT-AS1	MAPT antisense RNA 1	17q21.31	Mapped by Literature SNP
SPPL2C	signal peptide peptidase like 2C	17q21.31	Mapped by Literature SNP
CRHR1	corticotropin releasing hormone receptor 1	17q21.31	4(2/2/0)

SNPs in LD with rs4616318 (count: 3) View in gBrowse (chrCHR_HSCHR17_2_CTG5:45805388..45863062 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs81189	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.808[CEU]
rs12944712	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.957[CEU]
rs171440	intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	0.833[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)