SNP Report

Basic Info

Name	rs460000 dbSNP Ensembl
Location	chrCHR_HSCHR5_3_CTG1:1395361 - 1395361(-1)
Variant Alleles	G/T
Ancestral Allele	G
Minor Allele	T
Minor Allele Frequence	0.420327
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000270349, ENST00000621716, ENST00000630314); non_coding_transcript_variant(ENST00000630314)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Mick, E., 2008		T	TDT X²(df=1)=0.44, P-value = 0.529, OR (95% CI)=1...... TDT X²(df=1)=0.44, P-value = 0.529, OR (95% CI)=1.13(0.78-1.61) More...		Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SLC6A3	solute carrier family 6 (neurotransmitter transporter), member 3	5p15.3	11(5/6/0)

SNPs in LD with rs460000 (count: 8) View in gBrowse (chrCHR_HSCHR5_3_CTG1:1395361..1400382 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs464061	intron_variant; non_coding_transcript_variant	0.899[CEU]
rs393795	intron_variant; non_coding_transcript_variant	1.0[CEU]; 0.968[TSI]
rs460700	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs458860	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs409588	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs250682	intron_variant; non_coding_transcript_variant	1.0[CEU]; 1.0[TSI]
rs456774	intron_variant; non_coding_transcript_variant	0.956[CEU]
rs463379	intron_variant; non_coding_transcript_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)