SNP Report

Basic Info

Name	rs4467 dbSNP Ensembl
Location	chr22:35335252 - 35335252(1)
Variant Alleles	T/C
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.1252
Functional Annotation	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000456128, ENST00000620069); intron_variant(ENST00000382034, ENST00000404284, ENST00000411850, ENST00000424387, ENST00000425375, ENST00000447733, ENST00000449058, ENST00000491987); NMD_transcript_variant(ENST00000404284, ENST00000424387); non_coding_transcript_variant(ENST00000491987); upstream_gene_variant(ENST00000579518)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Potash, J. B., 2008	C/T		Family-based P-value = 0.85 for all BPAD subjects, family-ba...... Family-based P-value = 0.85 for all BPAD subjects, family-based P-value = 10 for BPAD subjects with psychotic symptoms, family-based P-value = 0.15 (3-marker sliding window with indicated marker first of the three), family-based P-value = 0.13 (3-marker sliding window with indicated marker first of the three using only those BPAD subjects with psychotic symptoms).Case-control P-value = 0.68 for all BPAD subjects, case-control P-value = 0.75 for BPAD subjects with psychotic symptoms, case-control P-value = 0.51 (3-marker sliding window with indicated marker first of the three), case-control P-value = 0.94 (3-marker sliding window with indicated marker first of the three using only those BPAD subjects with psychotic symptoms). More...		Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TOM1	target of myb1 (chicken)	22q13.1	1(1/0/0)
MIR3909	microRNA 3909	22	Mapped by Literature SNP

SNPs in LD with rs4467 (count: 1) View in gBrowse (chr22:35335252..35354987 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs17793276			0.864[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)