SNP Report

Basic Info

Name	rs4268468 dbSNP Ensembl
Location	chr11:90153116 - 90153116(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.243011
Functional Annotation	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000526637); intron_variant(ENST00000321955, ENST00000375944, ENST00000524501, ENST00000525171, ENST00000527493, ENST00000529090, ENST00000534061); NMD_transcript_variant(ENST00000527493); non_coding_transcript_variant(ENST00000524501, ENST00000529090)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Xu, W., 2014	T/C		P-value=6.08E-05 P-value=6.08E-05	Top 132 SNPs (showing suggestive association to BD in our CA...... Top 132 SNPs (showing suggestive association to BD in our CAMH family cohort: p<0.0001). More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NAALAD2	N-acetylated alpha-linked acidic dipeptidase 2	11q14.3-q21	1(0/1/0)

SNPs in LD with rs4268468 (count: 2) View in gBrowse (chr11:90121950..90153229 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs4393275		downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant	1.0[CEU]
rs10765243		downstream_gene_variant; upstream_gene_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)