SNP Report

Basic Info

Name	rs41274672 dbSNP Ensembl
Location	chr10:60071893 - 60071893(1)
Variant Alleles	C/G
Ancestral Allele	C
Minor Allele	G
Minor Allele Frequence	0.0247604
Functional Annotation	intron_variant; missense_variant; NMD_transcript_variant; upstream_gene_variant. Polyphen Annotation: benign(ENST00000280772, ENST00000621739) SIFT Annotation: tolerated - low confidence(ENST00000280772, ENST00000621739)
Consequence to Transcript	intron_variant(ENST00000355288, ENST00000373820, ENST00000373827, ENST00000503366, ENST00000511043, ENST00000610321, ENST00000616444); missense_variant(ENST00000280772, ENST00000621739); NMD_transcript_variant(ENST00000621739); upstream_gene_variant(ENST00000610901, ENST00000613207)
No. of Studies	2 (Positive: 0; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Dedman, A.,2012			Association analysis: for UCL1 sample, chi square=0.638, P-v...... Association analysis: for UCL1 sample, chi square=0.638, P-value = 0.42, OR=1.47; for UCL2 sample, chi square=1.226, P-value = 0.27, OR=0.65; for UCL1+UCL2 sample, chi square=0.0392, P-value = 0.84, OR=0.94 More...	No significant association was observed in BD. No significant association was observed in BD.	Negative
Fiorentino A., 2014	C/G		eurMLP=0.2 eurMLP=0.2	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10q21	17(13/3/1)

SNPs in LD with rs41274672 (count: 0) View in gBrowse (chr10:60071893..60071893 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)