SNP Report

Basic Info

Name	rs3821829 dbSNP Ensembl
Location	chr3:51702628 - 51702628(1)
Variant Alleles	T/A/C
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.0924521
Functional Annotation	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000444233, ENST00000457927); intron_variant(ENST00000341333, ENST00000395057, ENST00000415259, ENST00000416589, ENST00000457573, ENST00000463857, ENST00000489026, ENST00000493444, ENST00000611400, ENST00000614067); non_coding_transcript_variant(ENST00000463857, ENST00000489026, ENST00000493444); upstream_gene_variant(ENST00000296479, ENST00000395052, ENST00000419928, ENST00000464585, ENST00000475478)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Tsunoka, T.,2009	C/T	C	For BP: Genotypic association: P-value = 0.501, allelic asso...... For BP: Genotypic association: P-value = 0.501, allelic association: P-value = 0.713 More...	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GRM2	glutamate receptor, metabotropic 2	3p21.2	1(0/1/0)
TEX264	testis expressed 264	3p21	Mapped by Literature SNP

SNPs in LD with rs3821829 (count: 11) View in gBrowse (chr3:51506019..51721425 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs6775666	downstream_gene_variant; intron_variant; upstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs6787312	intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CHB]
rs6771491	5_prime_UTR_variant; downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs1055429	upstream_gene_variant	1.0[CHB]; 0.864[JPT]
rs11919197	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs4067	3_prime_UTR_variant; downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs4687721	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[JPT]
rs6800949	downstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs4355273	5_prime_UTR_variant; downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs6809155	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[JPT]
rs9311469		1.0[CHB]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Tsunoka, T.,2009	For MDD:Genotypic association:P-value = 0.869, allelic association:P-value = 0.924	No significant association was observed	Negative