BDgene

SNP Report

Basic Info
Name rs3794808 dbSNP Ensembl
Location chr17:30204775 - 30204775(1)
Variant Alleles C/T
Ancestral Allele C
Minor Allele C
Minor Allele Frequence 0.482029
Functional Annotation intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript intron_variant(ENST00000261707, ENST00000394821, ENST00000401766, ENST00000579221, ENST00000581633); NMD_transcript_variant(ENST00000579221); non_coding_transcript_variant(ENST00000581633); upstream_gene_variant(ENST00000578609)
No. of Studies 2 (Positive: 0; Negative: 2; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? YES

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Soronen, P.,2011 T/C For BD, allele, P-value = 0.4454 For BD, allele, P-value = 0.4454 No significant association was observed. No significant association was observed. Negative
Alaerts, M.,2009 A/G Allelic association P-value = 0.23; Genotypic association P-...... Allelic association P-value = 0.23; Genotypic association P-value = 0.23 More... No significant association was observed No significant association was observed Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 17q11.2 44(18/26/0)

SNPs in LD with rs3794808 (count: 29) View in gBrowse (chr17:30005089..30204995 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 29)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Soronen, P.,2011 For MDD, allele, P-value = 0.0046;For Mood, allele, P-value = 0.0115, OR=0.8167, P-value(perm)=0.432 Significant association was found. Positive

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016