SNP Report

Basic Info

Name	rs3784405 dbSNP Ensembl
Location	chr15:88144779 - 88144779(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.206869
Functional Annotation	intron_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000317501, ENST00000355254, ENST00000357724, ENST00000360948, ENST00000394480, ENST00000540489, ENST00000542733, ENST00000557856, ENST00000558676, ENST00000559188, ENST00000626019, ENST00000629765); upstream_gene_variant(ENST00000558776)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Athanasiu, L.,2011	C/T		Allelic association: OR=1.816, P-value = 7.38E-05, P-value(t...... Allelic association: OR=1.816, P-value = 7.38E-05, P-value(trend)=3.08E-05 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	15q24-q25	2(2/0/0)
MED28P6	mediator complex subunit 28 pseudogene 6	15q25.3	Mapped by Literature SNP

SNPs in LD with rs3784405 (count: 7) View in gBrowse (chr15:88123140..88194603 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs8035013	intron_variant	0.82[CEU]
rs11852633	intron_variant	0.874[CEU]
rs8025146	intron_variant	0.874[CEU]
rs1104918	intron_variant	0.82[CEU]; 0.843[TSI]
rs7179806	intron_variant	0.931[CEU]
rs4887208	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.897[CEU]
rs4887368	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.933[CEU]; 0.9[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)