SNP Report

Basic Info

Name	rs3778068 dbSNP Ensembl
Location	chr6:34060628 - 34060628(1)
Variant Alleles	C/G/T
Ancestral Allele	G
Minor Allele	C
Minor Allele Frequence	0.390775
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000374177, ENST00000374181, ENST00000455714, ENST00000535756, ENST00000538487, ENST00000544773, ENST00000545715, ENST00000609222, ENST00000609278, ENST00000609443, ENST00000609860); NMD_transcript_variant(ENST00000609278); non_coding_transcript_exon_variant(ENST00000609973); non_coding_transcript_variant(ENST00000545715, ENST00000609860, ENST00000609973); upstream_gene_variant(ENST00000609915)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Yosifova, A.,2009	C/G		Allelic association: P-value = 0.28 Allelic association: P-value = 0.28	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GRM4	glutamate receptor, metabotropic 4	6p21.3	2(2/0/0)

SNPs in LD with rs3778068 (count: 2) View in gBrowse (chr6:34060628..34061427 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs2451361		intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	1.0[CEU]
rs6901097		intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)