SNP Report

Basic Info

Name	rs3654 dbSNP Ensembl
Location	chr9:84815576 - 84815576(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.0800719
Functional Annotation	3_prime_UTR_variant; intron_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000359847, ENST00000395882); intron_variant(ENST00000277120, ENST00000304053, ENST00000323115, ENST00000376208, ENST00000376213, ENST00000376214)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Soronen, P.,2011	C/T		For BD, allele, P-value = 0.2716 For BD, allele, P-value = 0.2716	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	9q22.1	3(1/1/1)

SNPs in LD with rs3654 (count: 3) View in gBrowse (chr9:84806716..84815576 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs2013566	3_prime_UTR_variant; intron_variant	0.879[CEU]
rs3739804	intron_variant	0.879[CEU]
rs7019128	intron_variant	0.824[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Soronen, P.,2011	For MDD, allele, P-value = 0.054;For Mood, allele, P-value = 0.0425, OR=1.397, P-value(perm)=0.836	No significant association was observed.	Negative